Date of Award

1-1-2013

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Environmental Health Sciences

Content Description

1 online resource (xix, 301 pages) : illustrations (some color)

Dissertation/Thesis Chair

Patrick J Parsons

Committee Members

Ilham AlMahamid, Erin Bell, Dula Amarasiriwardena, Kurunthachalam Kannan

Keywords

blood, graphite furnace atomic absorption spectrometry, inductively coupled plasma mass spectrometry, manganese, teeth, urine, Manganese, Urine, Blood, Teeth, Furnace atomic absorption spectroscopy, Inductively coupled plasma mass spectrometry

Subject Categories

Environmental Health

Abstract

Manganese, as an essential trace element, is a cofactor in numerous enzymes that aid in bone growth, cholesterol synthesis, and carbohydrate metabolism. Manganese can become toxic with overexposure, potentially leading to neurodegenerative effects and the disease manganism. Manganese concentrations in blood and urine have been widely used in monitoring current exposure and now there is interest in using manganese concentrations in teeth for monitoring historical exposure, especially in utero and in early childhood.

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