Date of Award

1-1-2012

Language

English

Document Type

Master's Thesis

Degree Name

Master of Science (MS)

College/School/Department

Department of Biomedical Sciences

Content Description

1 online resource (x, 65 pages) : illustrations (some color)

Dissertation/Thesis Chair

Christopher A Fasano

Committee Members

Valerie Bolivar, Damian Shin, Sally Temple

Keywords

hESC, mDA, Neural, Parkinson's, Pluripotency, Embryonic stem cells, Parkinson's disease, Dopaminergic neurons

Subject Categories

Developmental Biology | Neuroscience and Neurobiology

Abstract

Translational biomedical research holds potential for the development of novel therapeutics for the treatment of injury, illness or disability. To better understand intrinsic cellular and molecular biology, human embryonic stem cells (hESCs) can be used as a tool. hESCs are pluripotent with the abilities to be held in a self-renewal state or become induced to a desired germ layer then to be later directed through differentiation.

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