Date of Award

1-1-2011

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Chemistry

Content Description

1 online resource (xii, 176 pages) : illustrations (some color)

Dissertation/Thesis Chair

Li Niu

Committee Members

Alexander Shekhtman, Carla Theimer, Greg A Lnenicka, Jayanti Pande

Keywords

Kainic acid, Glutamic acid, Neural transmission

Subject Categories

Biology | Neuroscience and Neurobiology | Physiology

Abstract

The ionotropic glutamate receptors are localized in the pre- and postsynaptic membrane of neurons and mediate the majority of fast excitatory synaptic transmission. These receptors are divided into three subtypes: α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainic acid, and N-methyl-D-aspartic acid (NMDA) receptors. My thesis work focused on AMPA and kainate receptor subtypes.

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