Date of Award
1-1-2018
Language
English
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
College/School/Department
Department of Nanoscale Science and Engineering
Program
Nanoscale Engineering
Content Description
1 online resource (ii, xvi, 122 pages) : illustrations (some color)
Dissertation/Thesis Chair
Nathaniel Cady
Committee Members
Janet Paluh, Michael Carpenter, Yubing Xie, James Williams
Keywords
Cancer Metastasis, Microfabrication, Microfluidics, Microscopy, Nanoengineering, Photoactuation, Tumors, Metastasis, Cancer, Carcinogenesis
Subject Categories
Nanoscience and Nanotechnology
Abstract
The tumor microenvironment (TME) is a heterogeneous collection of both healthy and pathological cells, whose complex interactions hold the key for understanding and overcoming cancer. Metastasis leverages these complex interactions into a sophisticated process by which single cells from the tumor disseminate into the blood and form new colonies in other organ systems. Subsequent formation of tumors throughout the body, as a direct result of metastatic events, is responsible for most deaths related to cancer, making metastasis a necessary target for cancer therapy.
Recommended Citation
Butt, Logan William, "The microfluidic intravital window : a tool for manipulation and imaging of the tumor microenvironment" (2018). Legacy Theses & Dissertations (2009 - 2024). 2010.
https://scholarsarchive.library.albany.edu/legacy-etd/2010