Date of Award
1-1-2017
Language
English
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
College/School/Department
Department of Chemistry
Content Description
1 online resource (ii, xi, 196 pages)
Dissertation/Thesis Chair
Mehmet V. Yigit
Committee Members
Alexander Shekhtman, Jia Sheng, Jan Halámek, Srivathsan V Ranganathan
Keywords
Biomarkers, DNA Nanobiotechnology, Heavy metal ions, Hybridization Chain Reaction, Liquid Biopsy, Reprogrammable, Colorimetric analysis, Biochemical markers, Nanostructured materials, Heavy metals
Subject Categories
Biochemistry | Biophysics | Nanoscience and Nanotechnology
Abstract
DNA nanotechnology has shown great promise in molecular diagnostic, bioanalytical and biomedical applications. The great challenge of detecting target analytes, biomarkers and small molecules, in molecular diagnostics is low yield sensitivity. To address this challenge, different nanomaterials have been used for a long time and to date there is no such cost-effective bioanalytical technique which can detect these target biomarkers (DNA, RNA, circulating DNA/miRNA) or environmental heavy metal ions (Hg2+ and Ag+) in a cost-effective and efficient manner.
Recommended Citation
Rana, Md Muhit, "Multifunctional nanomaterials utilizing hybridization chain reaction for molecular diagnostics and bioanalytical applications" (2017). Legacy Theses & Dissertations (2009 - 2024). 1922.
https://scholarsarchive.library.albany.edu/legacy-etd/1922