Date of Award

1-1-2017

Language

English

Document Type

Master's Thesis

Degree Name

Master of Science (MS)

College/School/Department

Department of Biomedical Sciences

Content Description

1 online resource (ii, iv, 50 pages) : illustrations (some color)

Dissertation/Thesis Chair

Sally Temple

Committee Members

Valerie Bolivar, Randy Morse

Keywords

Differentiation, Neural Induction, Stem Cells, Neural transmission, Stem cells, Cellular control mechanisms, Multipotent stem cells

Subject Categories

Neuroscience and Neurobiology

Abstract

The brain is one of the most complicated structures in the human body and its development is also elusive. Great strides have been made in expounding some of the complex mechanisms of neural development, which allows for the creation of innovative, less invasive, and more effective treatments for neurodevelopmental and neurodegenerative disorders. The advent of stem cell technology has brought therapy development for these disorders closer to a reality, as stem cells provide a platform to model early stages of human neural development. This is of great importance, as only through studying neurodevelopment will the various transcriptional and molecular components of the brain and their corresponding functions be exposed.

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