Date of Award

1-1-2016

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Chemistry

Content Description

1 online resource (ii. 266 pages) : illustrations (some color)

Dissertation/Thesis Chair

Eric Block

Committee Members

Robert Sheridan, Rabi Musah, Maksim Royzen, Ting Wang, Qiang Zhang

Keywords

ajoene, ajothiolane, alliin, garlic, olfaction, olfactory receptor, Garlic, Organosulfur compounds, Olfactory sensors, Smell, Olfactometry

Subject Categories

Analytical Chemistry | Biochemistry | Organic Chemistry

Abstract

Garlic is a very popular condiment that has been used around the world for centuries. It is also a source of a remarkably extensive range of organosulfur compounds, whose chemistry is the focus of this thesis. The central reaction in formation of these compounds is the enzymatic cleavage of alk(en)yl cysteine sulfoxides by alliinases, which leads to sulfenic acids. The latter can then undergo condensation and rearrangement into various organosulfur compounds. Three aspects of the chemistry of garlic have been investigated in this thesis.

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