Date of Award

1-1-2015

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Environmental Health Sciences

Content Description

1 online resource (x, 109 pages) : illustrations (some color)

Dissertation/Thesis Chair

Michael S Bloom

Committee Members

Victor Y Fujimoto, Richard W Browne, Erin M Bell, Recai M Yucel, Ying Wang

Keywords

Biological variability, Embryo quality, Follicular fluid, High density lipoprotein (HDL), Human ovarian follicles, in vitro fertilization (IVF), High density lipoproteins, Fertilization in vitro, Human, Human embryo

Subject Categories

Environmental Health | Epidemiology

Abstract

Follicular fluid (FF) is in direct contact with granulosa cells that surround a developing oocyte, and high density lipoprotein (HDL) is the sole lipoprotein found in FF. Therefore, we investigated 41 FF HDL particle components, including 26 HDL-cholesterol (HDL-C) subfractions measured for particle size, apolipoproteins, enzymes, and lipophilic micronutrients, in association with embryo quality on 180 women undergoing in vitro fertilization (IVF).

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