Date of Award

1-1-2015

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Environmental Health Sciences

Content Description

1 online resource (xiv, 270 pages) : color illustrations.

Dissertation/Thesis Chair

Patrick J Parsons

Committee Members

Thomas Semkow, Kurunthachalam Kannan, Sara Brenner, Fiona McNeill

Keywords

Alkaline Earth Elements, Bone, Parenteral Nutrition, Rare Earth Elements, Parenteral feeding, Parenteral solutions, Trace elements in the body, Rare earth metals, Alkaline earth metals, Bones

Subject Categories

Analytical Chemistry | Nutrition | Public Health

Abstract

This investigation focused on a unique collection of archived human bones obtained post-mortem from 7 patients, who had received long-term parenteral nutrition (PN) for up to 21 years. Parenterals are administered intravenously as a nutritional supplement, and may be contaminated with metals, which are completely absorbed into the blood compartment. Some metal contaminants may be deposited in the body’s reservoir for inorganic elements – bone.

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