Date of Award

1-1-2014

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Chemistry

Content Description

1 online resource (xv, 93 pages) : illustrations (some color)

Dissertation/Thesis Chair

Igor K. Lednev

Committee Members

Rabi A. Musah, Alexander Shekhtman, Carla A. Theimer, Earl A. Zimmerman

Keywords

Alzheimer's disease, artificial neural networks, blood serum, cerebrospinal fluid, multivariate statisitcs, Raman spectroscopy, Cerebrospinal fluid, Serum

Subject Categories

Analytical Chemistry | Biochemistry | Biostatistics

Abstract

The efficient and accurate diagnosis at the early stages of dementia is a key moment for effective treatment and productive research to find a new ways to combat the disease. It is especially true for Alzheimer's disease (AD) for which there is no effective cure, but several treatments are known to allow slowing down the degenerative processes. Alzheimer's disease (AD) displays only non-specific clinical symptoms of mental decline for decades after the initiation and is very challenging to differentiate even at the later stages when it becomes very aggressive. Despite the great need, current diagnostic tests are unable to diagnose different forms of dementia and other neurodegenerative diseases implicitly.

Share

COinS