"Light-Driven Chemistry: Photoswitch in RNA Activity Control and Develo" by Juncheng Li

ORCID

https://orcid.org/0009-0000-0643-5230

Date of Award

Spring 2025

Language

English

Embargo Period

4-30-2025

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Chemistry

Program

Chemistry

First Advisor

Ting Wang

Committee Members

Jia Sheng, Michael Yeung, Ken Halvorsen

Keywords

Photochemistry, RNA chemistry

Subject Categories

Organic Chemistry

Abstract

This dissertation is structured into two principal segments. The initial segment elucidates a series of synthetic works involving artificial molecules, specifically featuring the photosensitive azobenzene. These molecules facilitate remote control over the structure and functionality of biomolecules, with subsequent applications in regulating biological processes. The latter segment concentrates on the design and enhancement of organic photocatalysts, utilizing traditional acridine ions as a foundation. This section details the development of diverse organic photocatalyst-promoted processes, including photo Lewis acid catalysis, photo Brønsted acid catalysis, and photoredox reactions.

License

This work is licensed under the University at Albany Standard Author Agreement.

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