Date of Award

1-1-2010

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Chemistry

Content Description

1 online resource (viii, 109 pages)

Dissertation/Thesis Chair

Frank M Hauser

Committee Members

Rabi A Musah, Eric Block, Paul J Toscano, Robert L Brainard

Keywords

angucycline C104, benzo[a]anthraquinone, C-aryl glycoside synthesis, Hauser and Xu's route, Hauser's annulation, Glycosides

Subject Categories

Organic Chemistry

Abstract

The Hauser's annulation and Hauser and Xu's route for C-aryl glycoside synthesis were successfully employed to prepare the linear tetracyclic anthraquinone substituted C-aryl glycoside, galtamycin as well as bis C-aryl glycosides. Synthetic studies on angucycline C104 extended the utility of both methods to structures with angular tetracyclic framework.

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