Date of Award
1-1-2018
Language
English
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
College/School/Department
Department of Biomedical Sciences
Content Description
1 online resource (xvii, 252 pages) : color illustrations.
Dissertation/Thesis Chair
Kathleen A McDonough
Committee Members
Nicholas Mantis, William Lee, Marlene Belfort, Michelle Lennartz
Keywords
Bacterial pathogenesis, Cyclic-AMP signaling, Metabolism, Mycobacterium tuberculosis, Adenylic acid, Cellular signal transduction, Lipids, Fatty acids
Subject Categories
Microbiology | Molecular Biology
Abstract
Despite being the focus of intense research for many years Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains the deadliest bacterial pathogen plaguing mankind today. Humans are the sole host and reservoir for Mtb, and Mtb has coevolved closely with its human host for thousands of years. Mtb currently infects over two billion people worldwide and over 1.5 million people die from TB each year, arguably making Mtb the most successful bacterial pathogen on the planet.
Recommended Citation
Johnson, Richard Mcpherson, "Cyclic adenosine monophosphate signaling in mycobacterium tuberculosis : new insights into a universal second messenger" (2018). Legacy Theses & Dissertations (2009 - 2024). 2085.
https://scholarsarchive.library.albany.edu/legacy-etd/2085