Date of Award
5-2017
Document Type
Honors Thesis
Degree Name
Bachelor of Science
Department
Anthropology
Advisor/Committee Chair
Leah Seebald
Committee Member
Maksim Royzen
Abstract
Macrocycles are important organic ligands for encapsulating metal ions. This work describes the first step of a synthesis to create a bifunctional macrocyclic ligand suitable for nuclear magnetic resonance spectroscopy (NMR) studies. Cyclen is an organic macrocycle that contains twelve atoms total, with four nitrogen atoms incorporated into the cyclic backbone. Cyclen can be modified to coordinate a variety of metal ions by adding additional chelating arms. This synthesis is focused on functionalizing three of the donor nitrogens with carboxylate arms, while strategically leaving the fourth nitrogen available for further modification.
Recommended Citation
Noory, Hasina, "Synthesis of a Bifunctional Macrocycle" (2017). Anthropology. 22.
https://scholarsarchive.library.albany.edu/honorscollege_anthro/22