GLD-1 represses its puf mRNA targets prior to/at initiation of translation in the C.elegans germline
Date of Award
1-1-2012
Language
English
Document Type
Master's Thesis
Degree Name
Master of Science (MS)
College/School/Department
Department of Biological Sciences
Content Description
1 online resource (vi, 90 pages) : illustrations (some color)
Dissertation/Thesis Chair
Ben Szaro
Committee Members
Melinda Larsen, Douglas Conklin
Keywords
Gene expression, Genetic regulation, Repressors, Genetic, Caenorhabditis elegans, Germ cells, Messenger RNA
Subject Categories
Biology | Molecular Biology
Abstract
The C.elegans germline offers an ideal system to study posttranscriptional regulation of gene expression as it is a major mechanism through which the control over gene expression is achieved. GLD-1 (defective in GermLine Development) is a maxi-KH motif containing RNA binding protein that controls various aspects of germline development from decision over germcell proliferation vs. meiotic entry to the production of mature gametes suggesting that GLD-1 likely controls many mRNA targets.
Recommended Citation
Sarathy, Gautham, "GLD-1 represses its puf mRNA targets prior to/at initiation of translation in the C.elegans germline" (2012). Legacy Theses & Dissertations (2009 - 2024). 758.
https://scholarsarchive.library.albany.edu/legacy-etd/758