Date of Award

12-1-2023

Language

English

Document Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

College/School/Department

Department of Biological Sciences

Dissertation/Thesis Chair

PRASHANTH K RANGAN

Committee Members

Paolo E Forni, ChangHwan Lee, Erika A Bach

Keywords

Differentiation, Heterochromatin, Histone modifiers, Meiosis, Nucleopore complex, Transcription

Subject Categories

Biology

Abstract

Throughout the process of oogenesis, spanning from flies to humans, germ cells undergo a remarkable transformation, transitioning from a mitotic to a meiotic cell cycle. This intricate journey involves highly specialized cellular processes and culminates in the establishment of a maternal contribution, which plays a crucial role in promoting proper embryogenesis. Despite the significance of these transitions, their regulatory mechanisms have remained largely elusive, until now.

Included in

Biology Commons

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